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Pituitary adenylate cyclase activating polypeptide (PACAP) dilates cerebellar arteries through activation of large-conductance Ca(2+)-activated (BK) and ATP-sensitive (K(ATP)) K(+) channels

Pituitary adenylate cyclase activating polypeptide (PACAP) is a potent vasodilator of numerous vascular beds, including cerebral arteries. Although PACAP-induced cerebral artery dilation is suggested to be cyclic AMP (cAMP)-dependent, the downstream intracellular signaling pathways are still not ful...

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Hlavní autoři: Koide, Masayo, Syed, Arsalan U., Braas, Karen M., May, Victor, Wellman, George C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201911/
https://ncbi.nlm.nih.gov/pubmed/24744252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-014-0301-z
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