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Detection of minimal residual disease in NPM1-mutated acute myeloid leukemia by next-generation sequencing

Detection of minimal residual disease predicts adverse outcome in patients with acute myeloid leukemia. Currently, minimal residual disease may be detected by RQ-PCR or flow cytometry, both of which have practical and diagnostic limitations. Here, we describe a next-generation sequencing assay for m...

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Detalhes bibliográficos
Main Authors: Salipante, Stephen J., Fromm, Jonathan R., Shendure, Jay, Wood, Brent L., Wu, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201902/
https://ncbi.nlm.nih.gov/pubmed/24743218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2014.57
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