Novel Role of the Antimicrobial Peptide LL-37 in the Protection of Neutrophil Extracellular Traps against Degradation by Bacterial Nucleases

Neutrophil extracellular traps (NETs) have been described as a fundamental innate immune defence mechanism. They consist of a nuclear DNA backbone associated with different antimicrobial peptides (AMPs) which are able to engulf and kill pathogens. The AMP LL-37, a member of the cathelicidin family,...

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Bibliographic Details
Main Authors: Neumann, Ariane, Völlger, Lena, Berends, Evelien T.M., Molhoek, E. Margo, Stapels, Daphne A.C., Midon, Marika, Friães, Ana, Pingoud, Alfred, Rooijakkers, Suzan H.M., Gallo, Richard L., Mörgelin, Matthias, Nizet, Victor, Naim, Hassan Y., von Köckritz-Blickwede, Maren
Format: Artigo
Language:Inglês
Published: S. Karger AG 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201878/
https://ncbi.nlm.nih.gov/pubmed/25012862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000363699
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