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Ligand binding by the tandem glycine riboswitch depends on aptamer dimerization but not double ligand occupancy
The glycine riboswitch predominantly exists as a tandem structure, with two adjacent, homologous ligand-binding domains (aptamers), followed by a single expression platform. The recent identification of a leader helix, the inclusion of which eliminates cooperativity between the aptamers, has reopene...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201829/ https://ncbi.nlm.nih.gov/pubmed/25246650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.047266.114 |
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