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Rejection of tmRNA·SmpB after GTP hydrolysis by EF-Tu on ribosomes stalled on intact mRNA

Messenger RNAs lacking a stop codon trap ribosomes at their 3′ ends, depleting the pool of ribosomes available for protein synthesis. In bacteria, a remarkable quality control system rescues and recycles stalled ribosomes in a process known as trans-translation. Acting as a tRNA, transfer-messenger...

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Detalhes bibliográficos
Main Authors: Kurita, Daisuke, Miller, Mickey R., Muto, Akira, Buskirk, Allen R., Himeno, Hyouta
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201823/
https://ncbi.nlm.nih.gov/pubmed/25246654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045773.114
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