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Power analysis and sample size estimation for RNA-Seq differential expression

It is crucial for researchers to optimize RNA-seq experimental designs for differential expression detection. Currently, the field lacks general methods to estimate power and sample size for RNA-Seq in complex experimental designs, under the assumption of the negative binomial distribution. We simul...

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Autori principali: Ching, Travers, Huang, Sijia, Garmire, Lana X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201821/
https://ncbi.nlm.nih.gov/pubmed/25246651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.046011.114
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