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Measuring the Effect of Inter-Study Variability on Estimating Prediction Error

BACKGROUND: The biomarker discovery field is replete with molecular signatures that have not translated into the clinic despite ostensibly promising performance in predicting disease phenotypes. One widely cited reason is lack of classification consistency, largely due to failure to maintain perform...

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Detalhes bibliográficos
Main Authors: Ma, Shuyi, Sung, Jaeyun, Magis, Andrew T., Wang, Yuliang, Geman, Donald, Price, Nathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201588/
https://ncbi.nlm.nih.gov/pubmed/25330348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110840
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