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Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases

In support of accurate neuropeptide identification in mass spectrometry experiments, novel Monte Carlo permutation testing was used to compute significance values. Testing was based on k-permuted decoy databases, where k denotes the number of permutations. These databases were integrated with a rang...

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Detalhes bibliográficos
Main Authors: Akhtar, Malik N., Southey, Bruce R., Andrén, Per E., Sweedler, Jonathan V., Rodriguez-Zas, Sandra L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201571/
https://ncbi.nlm.nih.gov/pubmed/25329667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111112
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