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Split-Cre Complementation Restores Combination Activity on Transgene Excision in Hair Roots of Transgenic Tobacco

The Cre/loxP system is increasingly exploited for genetic manipulation of DNA in vitro and in vivo. It was previously reported that inactive ‘‘split-Cre’’ fragments could restore Cre activity in transgenic mice when overlapping co-expression was controlled by two different promoters. In this study,...

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Detalhes bibliográficos
Main Authors: Wen, Mengling, Gao, Yuan, Wang, Lijun, Ran, Lingyu, Li, Jiahui, Luo, Keming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201524/
https://ncbi.nlm.nih.gov/pubmed/25329460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110290
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