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Evaluation of the Role of G Protein-Coupled Receptor Kinase 3 in Desensitization of Mouse Odorant Receptors in a Mammalian Cell Line and in Olfactory Sensory Neurons

Thousands of odors are sensed and discriminated by G protein-coupled odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs). G protein-coupled receptor kinases (GRKs) may have a role in desensitization of ORs. However, whether ORs are susceptible to agonist-dependent desensitization a...

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Detalhes bibliográficos
Main Authors: Kato, Aya, Reisert, Johannes, Ihara, Sayoko, Yoshikawa, Keiichi, Touhara, Kazushige
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201305/
https://ncbi.nlm.nih.gov/pubmed/25313015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chemse/bju050
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