Conversion of Partially Reprogrammed Cells to Fully Pluripotent Stem Cells Is Associated with Further Activation of Stem Cell Maintenance- and Gamete Generation-Related Genes

Somatic cells are reprogrammed to induced pluripotent stem cells (iPSCs) by overexpression of a combination of defined transcription factors. We generated iPSCs from mouse embryonic fibroblasts (with Oct4-GFP reporter) by transfection of pCX-OSK-2A (Oct4, Sox2, and Klf4) and pCX-cMyc vectors. We cou...

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Hlavní autoři: Kim, Jong Soo, Choi, Hyun Woo, Choi, Sol, Seo, Han Geuk, Moon, Sung-Hwan, Chung, Hyung-Min, Do, Jeong Tae
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2014
Témata:
Original Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201244/
https://ncbi.nlm.nih.gov/pubmed/24892478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0020
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