LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones.
The rat glucocorticoid receptor confers hormone-dependent transcriptional enhancement when expressed in yeast, thereby enabling the genetic identification of nonreceptor proteins that function in the hormone signal-transduction pathway. We isolated a yeast mutant, lem1, with increased sensitivity to...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1995
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42012/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753868/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4701 |
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