Loss of Apm1, the μ1 Subunit of the Clathrin-Associated Adaptor-Protein-1 Complex, Causes Distinct Phenotypes and Synthetic Lethality with Calcineurin Deletion in Fission Yeast

Calcineurin is a highly conserved regulator of Ca(2+) signaling in eukaryotes. In fission yeast, calcineurin is not essential for viability but is required for cytokinesis and Cl(-) homeostasis. In a genetic screen for mutations that are synthetically lethal with calcineurin deletion, we isolated a...

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Hauptverfasser: Kita, Ayako, Sugiura, Reiko, Shoji, Hiromi, He, Yi, Deng, Lu, Lu, Yabin, Sio, Susie O., Takegawa, Kaoru, Sakaue, Motoyoshi, Shuntoh, Hisato, Kuno, Takayoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2004
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC420114/
https://ncbi.nlm.nih.gov/pubmed/15047861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-09-0659
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