Endocannabinoid 2-Arachidonoylglycerol Self-Administration by Sprague-Dawley Rats and Stimulation of in vivo Dopamine Transmission in the Nucleus Accumbens Shell

2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB(1) receptors and is synthesized on demand from 2-arachidonate-containing phosphoinositides by the action of diacylglycerol lipase in response to increased intracellular calcium. Several studies indicate that t...

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Bibliographic Details
Main Authors: De Luca, Maria Antonietta, Valentini, Valentina, Bimpisidis, Zisis, Cacciapaglia, Fabio, Caboni, Pierluigi, Di Chiara, Gaetano
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Psychiatry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201088/
https://ncbi.nlm.nih.gov/pubmed/25368584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2014.00140
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