DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

N-methyl-D-aspartate glutamate receptors (NMDARs) play a pivotal role in neural development and synaptic plasticity, as well as in neurological disease. Since NMDARs exert their function at the cell surface, their density in the plasma membrane is finely tuned by a plethora of molecules that regulat...

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Detalhes bibliográficos
Main Authors: Grau, Cristina, Arató, Krisztina, Fernández-Fernández, José M., Valderrama, Aitana, Sindreu, Carlos, Fillat, Cristina, Ferrer, Isidre, de la Luna, Susana, Altafaj, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201086/
https://ncbi.nlm.nih.gov/pubmed/25368549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00331
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