Phase 2 study of safety and efficacy of nimotuzumab in pediatric patients with progressive diffuse intrinsic pontine glioma

BACKGROUND: The prognosis of diffuse intrinsic pontine glioma (DIPG) remains poor, with no drug proven to be effective. METHODS: Patients with clinically and radiologically confirmed, centrally reviewed DIPG, who had failed standard first-line therapy were eligible for this multicenter phase II tria...

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Detalhes bibliográficos
Main Authors: Bartels, Ute, Wolff, Johannes, Gore, Lia, Dunkel, Ira, Gilheeney, Stephen, Allen, Jeffrey, Goldman, Stewart, Yalon, Michal, Packer, Roger J., Korones, David N., Smith, Amy, Cohen, Kenneth, Kuttesch, John, Strother, Douglas, Baruchel, Sylvain, Gammon, Janet, Kowalski, Mark, Bouffet, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Pediatric Neuro-Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201068/
https://ncbi.nlm.nih.gov/pubmed/24847085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou091
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