Experience With Afatinib in Patients With Non-Small Cell Lung Cancer Progressing After Clinical Benefit From Gefitinib and Erlotinib

BACKGROUND. Afatinib, an irreversible ErbB family blocker, demonstrated superiority to chemotherapy as first-line treatment in patients with EGFR-mutated non-small cell lung cancer (NSCLC). Afatinib is also active in patients progressing on EGFR tyrosine kinase inhibitors (EGFR-TKIs). We report the...

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Bibliographic Details
Main Authors: Schuler, Martin, Fischer, Jürgen R., Grohé, Christian, Gütz, Sylvia, Thomas, Michael, Kimmich, Martin, Schneider, Claus-Peter, Laack, Eckart, Märten, Angela
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2014
Subjects:
Lung Cancer
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200993/
https://ncbi.nlm.nih.gov/pubmed/25232040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0103
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