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The Palmitoyltransferase of the Cation-dependent Mannose 6-Phosphate Receptor Cycles between the Plasma Membrane and Endosomes

The cation-dependent mannose 6-phosphate receptor (CD-MPR) mediates the transport of lysosomal enzymes from the trans-Golgi network to endosomes. Evasion of lysosomal degradation of the CD-MPR requires reversible palmitoylation of a cysteine residue in its cytoplasmic tail. Because palmitoylation is...

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Autors principals: Stöckli, Jacqueline, Rohrer, Jack
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC420087/
https://ncbi.nlm.nih.gov/pubmed/15034140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-11-0808
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