Synthesis, Anticonvulsant, Sedative and Anxiolytic Activities of Novel Annulated Pyrrolo[1,4]benzodiazepines

Four new pentacyclic benzodiazepine derivatives (PBDTs 13–16) were synthesized by conventional thermal heating and microwave-assisted intramolecular cyclocondensation. Their anticonvulsant, sedative and anxiolytic activities were evaluated by drug-induced convulsion models, a pentobarbital-induced h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sorra, Kumaraswamy, Chen, Chien-Shu, Chang, Chi-Fen, Pusuluri, Srinivas, Mukkanti, Khagga, Wu, Chi-Rei, Chuang, Ta-Hsien
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200843/
https://ncbi.nlm.nih.gov/pubmed/25238414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150916500
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