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Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cells

BACKGROUND: The transcription factor Pax8 is expressed during thyroid development and is involved in the morphogenesis of the thyroid gland and maintenance of the differentiated phenotype. In particular, Pax8 has been shown to regulate genes that are considered markers of thyroid differentiation. Re...

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Autors principals: Filippone, Maria Grazia, Di Palma, Tina, Lucci, Valeria, Zannini, Mariastella
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200477/
https://ncbi.nlm.nih.gov/pubmed/25270402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-15-21
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