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Differential effects of omega-3 fatty acid docosahexaenoic acid and palmitate on the circadian transcriptional profile of clock genes in immortalized hypothalamic neurons

Diets high in saturated fatty acids (SFAs) are associated with the development of circadian dysregulation, obesity, and Type 2 diabetes mellitus. Conversely, polyunsaturated fatty acids (PUFAs) have recently been identified to improve insulin sensitivity, reduce weight gain, and relieve obesity-indu...

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Autors principals: Greco, James A., Oosterman, Johanneke E., Belsham, Denise D.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200380/
https://ncbi.nlm.nih.gov/pubmed/25144192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00100.2014
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