Mitochondrial depolarization and electrophysiological changes during ischemia in the rabbit and human heart

Instability of the inner mitochondrial membrane potential (ΔΨ(m)) has been implicated in electrical dysfunction, including arrhythmogenesis during ischemia-reperfusion. Monitoring ΔΨ(m) has led to conflicting results, where depolarization has been reported as sporadic and as a propagating wave. The...

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Detalhes bibliográficos
Main Authors: Sulkin, Matthew S., Boukens, Bas J., Tetlow, Megan, Gutbrod, Sarah R., Ng, Fu Siong, Efimov, Igor R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Cardiac Excitation and Contraction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200335/
https://ncbi.nlm.nih.gov/pubmed/25128175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00437.2014
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