Eicosanomic profiling reveals dominance of the epoxygenase pathway in human amniotic fluid at term in spontaneous labor

Lipid mediators play an important role in reproductive biology, especially, in parturition. Enhanced biosynthesis of eicosanoids, such as prostaglandin E(2) (PGE(2)) and PGF(2)α, precedes the onset of labor as a result of increased expression of inducible cyclooxygenase 2 (COX-2) in placental tissue...

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Detalhes bibliográficos
Main Authors: Maddipati, Krishna Rao, Romero, Roberto, Chaiworapongsa, Tinnakorn, Zhou, Sen-Lin, Xu, Zhonghui, Tarca, Adi L., Kusanovic, Juan Pedro, Munoz, Hernan, Honn, Kenneth V.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200329/
https://ncbi.nlm.nih.gov/pubmed/25059230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-254383
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