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Role of caveolin 1 in AT(1a) receptor-mediated uptake of angiotensin II in the proximal tubule of the kidney

Caveolin 1 (CAV-1) functions not only as a constitutive scaffolding protein of caveolae but also as a vesicular transporter and signaling regulator. In the present study, we tested the hypothesis that CAV-1 knockout (CAV-1 KO) inhibits ANG II type 1 [AT(1) (AT(1a))] receptor-mediated uptake of ANG I...

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Autori principali: Li, Xiao C., Gu, Victor, Miguel-Qin, Elise, Zhuo, Jia L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200294/
https://ncbi.nlm.nih.gov/pubmed/25164083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00199.2014
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