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Rapid Mechanisms for Generating Genome Diversity: Whole Ploidy Shifts, Aneuploidy, and Loss of Heterozygosity

Human fungal pathogens can exist in a variety of ploidy states, including euploid and aneuploid forms. Ploidy change has a major impact on phenotypic properties, including the regulation of interactions with the human host. In addition, the rapid emergence of drug-resistant isolates is often associa...

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Autors principals: Bennett, Richard J., Forche, Anja, Berman, Judith
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200206/
https://ncbi.nlm.nih.gov/pubmed/25081629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a019604
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