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Insights into the Genetic Structure of Congenital Heart Disease from Human and Murine Studies on Monogenic Disorders
Study of monogenic congenital heart disease (CHD) has provided entry points to gain new understanding of heart development and the molecular pathogenesis of CHD. In this review, we discuss monogenic CHD caused by mutations of the cardiac transcription factor genes NKX2-5 and GATA4. Detailed investig...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200204/ https://ncbi.nlm.nih.gov/pubmed/25274754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a013946 |
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