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Identification of CRYM as a Candidate Responsible for Nonsyndromic Deafness, through cDNA Microarray Analysis of Human Cochlear and Vestibular Tissues

Through cDNA microarray analysis of gene expression in human cochlea and vestibule, we detected strong expression of μ-crystallin (CRYM; also known as “NADP-regulated thyroid hormone-binding protein”) only in these inner-ear tissues. In a subsequent search for mutations of CRYM, among 192 patients w...

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Autori principali: Abe, Satoko, Katagiri, Toyomasa, Saito-Hisaminato, Akihiko, Usami, Shin-ichi, Inoue, Yasuhiro, Tsunoda, Tatsuhiko, Nakamura, Yusuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC420014/
https://ncbi.nlm.nih.gov/pubmed/12471561
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