Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization

Endomitosis is a unique megakaryocyte (MK) differentiation process that is the consequence of a late cytokinesis failure associated with a contractile ring defect. Evidence from in vitro studies has revealed the distinct roles of 2 nonmuscle myosin IIs (NMIIs) on MK endomitosis: only NMII-B (MYH10),...

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Autores principales: Badirou, Idinath, Pan, Jiajia, Legrand, Céline, Wang, Aibing, Lordier, Larissa, Boukour, Siham, Roy, Anita, Vainchenker, William, Chang, Yunhua
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199958/
https://ncbi.nlm.nih.gov/pubmed/25185263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-584995
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