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WAVE3-NFκB Interplay Is Essential for the Survival and Invasion of Cancer Cells

The WAVE3 cytoskeletal protein promotes cancer invasion and metastasis. We have shown that the WAVE3-mediated activation of cancer cell invasion is due, in part, to its regulation of expression and activity of key metalloproteinases (MMPs), including MMP9, which is centrally involved in invadopodia-...

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Autors principals: Davuluri, Gangarao, Augoff, Katarzyna, Schiemann, William P., Plow, Edward F., Sossey-Alaoui, Khalid
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199728/
https://ncbi.nlm.nih.gov/pubmed/25329315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110627
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