Endogenous Retrovirus Insertion in the KIT Oncogene Determines White and White spotting in Domestic Cats

The Dominant White locus (W) in the domestic cat demonstrates pleiotropic effects exhibiting complete penetrance for absence of coat pigmentation and incomplete penetrance for deafness and iris hypopigmentation. We performed linkage analysis using a pedigree segregating White to identify KIT (Chr. B...

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Autores principales: David, Victor A., Menotti-Raymond, Marilyn, Wallace, Andrea Coots, Roelke, Melody, Kehler, James, Leighty, Robert, Eizirik, Eduardo, Hannah, Steven S., Nelson, George, Schäffer, Alejandro A., Connelly, Catherine J., O’Brien, Stephen J., Ryugo, David K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199695/
https://ncbi.nlm.nih.gov/pubmed/25085922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.013425
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