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Genetics of hypertrophic cardiomyopathy: advances and pitfalls in molecular diagnosis and therapy

Hypertrophic cardiomyopathy (HCM) is a primary disease of the cardiac muscle that occurs mainly due to mutations (>1,400 variants) in genes encoding for the cardiac sarcomere. HCM, the most common familial form of cardiomyopathy, affecting one in every 500 people in the general population, is typ...

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Detalhes bibliográficos
Main Authors: Roma-Rodrigues, Catarina, Fernandes, Alexandra R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199654/
https://ncbi.nlm.nih.gov/pubmed/25328416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S49126
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