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Overexpression of Glutathione Transferase E7 in Drosophila Differentially Impacts Toxicity of Organic Isothiocyanates in Males and Females

Organic isothiocyanates (ITCs) are allelochemicals produced by plants in order to combat insects and other herbivores. The compounds are toxic electrophiles that can be inactivated and conjugated with intracellular glutathione in reactions catalyzed by glutathione transferases (GSTs). The Drosophila...

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Hlavní autoři: Mazari, Aslam M. A., Dahlberg, Olle, Mannervik, Bengt, Mannervik, Mattias
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199631/
https://ncbi.nlm.nih.gov/pubmed/25329882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110103
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