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Break-Induced Replication Requires DNA Damage-Induced Phosphorylation of Pif1 and Leads to Telomere Lengthening

Broken replication forks result in DNA breaks that are normally repaired via homologous recombination or break induced replication (BIR). Mild insufficiency in the replicative ligase Cdc9 in budding yeast Saccharomyces cerevisiae resulted in a population of cells with persistent DNA damage, most lik...

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Bibliografiske detaljer
Main Authors: Vasianovich, Yulia, Harrington, Lea A., Makovets, Svetlana
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199488/
https://ncbi.nlm.nih.gov/pubmed/25329304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004679
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