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Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor.

Two endocytic receptors, the low density lipoprotein (LDL) receptor (LDLR) and the LDLR-related protein (LRP), are thought to act in concert in the hepatic uptake of partially metabolized dietary lipoproteins, the chylomicron remnants. We have evaluated the role of these two receptors in the hepatic...

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Autores principales: Herz, J, Qiu, S Q, Oesterle, A, DeSilva, H V, Shafi, S, Havel, R J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC41994/
https://ncbi.nlm.nih.gov/pubmed/7753850
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