Large-scale identification of chemically induced mutations in Drosophila melanogaster

Forward genetic screens using chemical mutagens have been successful in defining the function of thousands of genes in eukaryotic model organisms. The main drawback of this strategy is the time-consuming identification of the molecular lesions causative of the phenotypes of interest. With whole-geno...

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Detalhes bibliográficos
Main Authors: Haelterman, Nele A., Jiang, Lichun, Li, Yumei, Bayat, Vafa, Sandoval, Hector, Ugur, Berrak, Tan, Kai Li, Zhang, Ke, Bei, Danqing, Xiong, Bo, Charng, Wu-Lin, Busby, Theodore, Jawaid, Adeel, David, Gabriela, Jaiswal, Manish, Venken, Koen J.T., Yamamoto, Shinya, Chen, Rui, Bellen, Hugo J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199363/
https://ncbi.nlm.nih.gov/pubmed/25258387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.174615.114
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