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Targeting delivery of drugs in the vascular system

Delivery and effects of therapeutics remain suboptimal. Most drugs do not have affinity to their targets. Biotherapeutics including enzymes and genetic materials require specific sub-cellular addressing not attainable naturally. Endothelium, lining the luminal surface of blood vessels, represents a...

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Autors principals: Muzykantov, Vladimir, Muro, Silvia
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199305/
https://ncbi.nlm.nih.gov/pubmed/25328360
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