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The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism

The formation of a laminar structure such as the mammalian neocortex relies on the coordinated migration of different subtypes of excitatory pyramidal neurons in specific layers. Cyclin-dependent kinase 5 (Cdk5) is a master regulator of pyramidal neuron migration. Recently, we have shown that Cdk5 b...

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Autores principales: Jacobshagen, Moritz, Niquille, Mathieu, Chaumont-Dubel, Séverine, Marin, Philippe, Dayer, Alexandre
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199128/
https://ncbi.nlm.nih.gov/pubmed/25078650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108043
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