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Metformin induces a prompt decrease in LH-stimulated testosterone response in women with PCOS independent of its insulin-sensitizing effects

BACKGROUND: The use of insulin-sensitizing drugs has been shown to improve both the reproductive and the metabolic aspects of PCOS. However, the mechanisms by which metformin exerts its effects in PCOS are still not completely understood. There is growing evidence of a direct effect of metformin on...

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Autores principales: Kurzthaler, Dorothea, Hadziomerovic-Pekic, Dijana, Wildt, Ludwig, Seeber, Beata E
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199060/
https://ncbi.nlm.nih.gov/pubmed/25304843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-12-98
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