Genome-Wide Analysis of mRNA Stability Using Transcription Inhibitors and Microarrays Reveals Posttranscriptional Control of Ribosome Biogenesis Factors

Using DNA microarrays, we compared global transcript stability profiles following chemical inhibition of transcription to rpb1-1 (a temperature-sensitive allele of yeast RNA polymerase II). Among the five inhibitors tested, the effects of thiolutin and 1,10-phenanthroline were most similar to rpb1-1...

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Detalhes bibliográficos
Main Authors: Grigull, Jörg, Mnaimneh, Sanie, Pootoolal, Jeffrey, Robinson, Mark D., Hughes, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419893/
https://ncbi.nlm.nih.gov/pubmed/15169913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5534-5547.2004
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