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Genome-Wide Analysis of mRNA Stability Using Transcription Inhibitors and Microarrays Reveals Posttranscriptional Control of Ribosome Biogenesis Factors

Using DNA microarrays, we compared global transcript stability profiles following chemical inhibition of transcription to rpb1-1 (a temperature-sensitive allele of yeast RNA polymerase II). Among the five inhibitors tested, the effects of thiolutin and 1,10-phenanthroline were most similar to rpb1-1...

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Udgivet i:Mol Cell Biol
Principais autores: Grigull, Jörg, Mnaimneh, Sanie, Pootoolal, Jeffrey, Robinson, Mark D., Hughes, Timothy R.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419893/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15169913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.12.5534-5547.2004
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