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An Efficient Estimator of the Mutation Parameter and Analysis of Polymorphism from the 1000 Genomes Project

The mutation parameter θ is fundamental and ubiquitous in the analysis of population samples of DNA sequences. This paper presents a new highly efficient estimator of θ by utilizing the phylogenetic information among distinct alleles in a sample of DNA sequences. The new estimator, called Allelic BL...

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Detalles Bibliográficos
Autor principal: Fu, Yunxin
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198917/
https://ncbi.nlm.nih.gov/pubmed/25055200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5030561
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