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The Balance of Cell Surface and Soluble Type III TGF-β Receptor Regulates BMP Signaling in Normal and Cancerous Mammary Epithelial Cells()

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily that are over-expressed in breast cancer, with context dependent effects on breast cancer pathogenesis. The type III TGF-β receptor (TβRIII) mediates BMP signaling. While TβRIII expression is lost during breast cancer progressio...

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Detalhes bibliográficos
Main Authors: Gatza, Catherine E., Elderbroom, Jennifer L., Oh, Sun Young, Starr, Mark D., Nixon, Andrew B., Blobe, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198744/
https://ncbi.nlm.nih.gov/pubmed/25077702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.05.008
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