Mutations in a Partitioning Protein and Altered Chromatin Structure at the Partitioning Locus Prevent Cohesin Recruitment by the Saccharomyces cerevisiae Plasmid and Cause Plasmid Missegregation

The 2μm circle is a highly persistent “selfish” DNA element resident in the Saccharomyces cerevisiae nucleus whose stability approaches that of the chromosomes. The plasmid partitioning system, consisting of two plasmid-encoded proteins, Rep1p and Rep2p, and a cis-acting locus, STB, apparently feeds...

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Autores principales: Yang, Xian-Mei, Mehta, Shwetal, Uzri, Dina, Jayaram, Makkuni, Velmurugan, Soundarapandian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
DNA Dynamics and Chromosome Structure
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC419871/
https://ncbi.nlm.nih.gov/pubmed/15169893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.12.5290-5303.2004
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