KRAS and BRAF mutational status in colon cancer from Albanian patients

BACKGROUND: Numerous clinical studies have shown that anti-EGFR therapies are effective only in a subset of patients with colorectal cancer. Mutations in the KRAS and BRAF genes have been confirmed as negative predictors of the response to EGFR-targeted therapies. In this study we evaluated KRAS and...

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Autores principales: Martinetti, Daniela, Costanzo, Rosario, Kadare, Shahin, Alimehmeti, Mehdiu, Colarossi, Cristina, Canzonieri, Vincenzo, Berretta, Massimiliano, Memeo, Lorenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198623/
https://ncbi.nlm.nih.gov/pubmed/25267307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-014-0187-7
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