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A NOVEL METHOD FOR ANALYSIS OF HUMAN T CELL REPERTOIRES BY REAL-TIME PCR

T lymphocyte responses to challenges with multiple pathogens depend on the diversity of their T cell receptors (TcRs) that are heteroduplexes of alpha and beta chains. The regions of alpha and beta chains that define TcR specificity are encoded by rearranged variable (V) and joining (J) genes that a...

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Bibliographic Details
Main Authors: Wettstein, Peter J., Borson, Nancy D., Kay, Neil E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198569/
https://ncbi.nlm.nih.gov/pubmed/24983878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.06.013
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