A Staphylococcus aureus TIR Domain Protein Virulence Factor Blocks TLR2-Mediated NF-κB Signaling

Signaling through Toll-like receptors (TLRs), crucial molecules in the induction of host defense responses, requires adaptor proteins that contain a Toll/interleukin-1 receptor (TIR) domain. The pathogen Staphylococcus aureus produces several innate immune-evasion molecules that interfere with the h...

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Detalhes bibliográficos
Main Authors: Askarian, Fatemeh, van Sorge, Nina M., Sangvik, Maria, Beasley, Federico C., Henriksen, Jørn R., Sollid, Johanna U.E., van Strijp, Jos A.G., Nizet, Victor, Johannessen, Mona
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198549/
https://ncbi.nlm.nih.gov/pubmed/24481289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000357618
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