Endothelial Interleukin-6 defines the tumorigenic potential of primary human cancer stem cells

Head and neck squamous cell carcinomas (HNSCC) contain a small sub-population of stem cells endowed with unique capacity to generate tumors. These cancer stem cells (CSC) are localized in perivascular niches and rely on crosstalk with endothelial cells for survival and self-renewal, but the mechanis...

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Detalhes bibliográficos
Main Authors: Krishnamurthy, Sudha, Warner, Kristy A., Dong, Zhihong, Imai, Atsushi, Nör, Carolina, Ward, Brent B., Helman, Joseph I., Taichman, Russell S., Bellile, Emily L., McCauley, Laurie K., Polverini, Peter J., Prince, Mark E., Wicha, Max S., Nör, Jacques E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198458/
https://ncbi.nlm.nih.gov/pubmed/25078284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1793
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