Endothelial Interleukin-6 defines the tumorigenic potential of primary human cancer stem cells

Head and neck squamous cell carcinomas (HNSCC) contain a small sub-population of stem cells endowed with unique capacity to generate tumors. These cancer stem cells (CSC) are localized in perivascular niches and rely on crosstalk with endothelial cells for survival and self-renewal, but the mechanis...

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Autori principali: Krishnamurthy, Sudha, Warner, Kristy A., Dong, Zhihong, Imai, Atsushi, Nör, Carolina, Ward, Brent B., Helman, Joseph I., Taichman, Russell S., Bellile, Emily L., McCauley, Laurie K., Polverini, Peter J., Prince, Mark E., Wicha, Max S., Nör, Jacques E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198458/
https://ncbi.nlm.nih.gov/pubmed/25078284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1793
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