Regulation of Mitochondrial Function and Cellular Energy Metabolism by Protein Kinase C-λ/ι: A Novel Mode of Balancing Pluripotency

Pluripotent stem cells (PSCs) contain functionally immature mitochondria and rely upon high rates of glycolysis for their energy requirements. Thus, altered mitochondrial function and promotion of aerobic glycolysis is key to maintain and induce pluripotency. However, signaling mechanisms that regul...

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Bibliografiske detaljer
Main Authors: Mahato, Biraj, Home, Pratik, Rajendran, Ganeshkumar, Paul, Arindam, Saha, Biswarup, Ganguly, Avishek, Ray, Soma, Roy, Nairita, Swerdlow, Russell H., Paul, Soumen
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198455/
https://ncbi.nlm.nih.gov/pubmed/25142417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1817
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