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Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition

The transcription factor TWIST1 is a basic helix-loop-helix protein that regulates epithelial-mesenchymal transition (EMT) in early embryonic morphogenesis, cancer development, and cancer metastasis. The regulation of TWIST1 remains poorly understood. Recently, we found that autophagy deficiency sta...

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Détails bibliographiques
Auteurs principaux: Qiang, Lei, He, Yu-Ying
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198370/
https://ncbi.nlm.nih.gov/pubmed/25126736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.32171
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