Human Valacyclovir Hydrolase/Biphenyl Hydrolase-Like Protein Is a Highly Efficient Homocysteine Thiolactonase

Homocysteinylation of lysine residues by homocysteine thiolactone (HCTL), a reactive homocysteine metabolite, results in protein aggregation and malfunction, and is a well-known risk factor for cardiovascular, autoimmune and neurological diseases. Human plasma paraoxonase-1 (PON1) and bleomycin hydr...

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Autors principals: Marsillach, Judit, Suzuki, Stephanie M., Richter, Rebecca J., McDonald, Matthew G., Rademacher, Peter M., MacCoss, Michael J., Hsieh, Edward J., Rettie, Allan E., Furlong, Clement E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198189/
https://ncbi.nlm.nih.gov/pubmed/25333274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110054
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