Loss and dysfunction of Vδ2(+) γδ T cells is associated with clinical tolerance to malaria

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The Vδ2(+) subset of γδ T cells possess intrinsic reactivity to malaria antigens, can mediate killing of P. falciparum merozoites, and expand mark...

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Autors principals: Jagannathan, Prasanna, Kim, Charlie C., Greenhouse, Bryan, Nankya, Felistas, Bowen, Katherine, Eccles-James, Ijeoma, Muhindo, Mary K, Arinaitwe, Emmanuel, Tappero, Jordan W., Kamya, Moses R, Dorsey, Grant, Feeney, Margaret E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198150/
https://ncbi.nlm.nih.gov/pubmed/25163477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009793
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